We are seeking a PhD student to investigate the role of Adhesion GPCRs in adipocyte function. (pdf)
Adhesion GPCRs are the second largest group of cell surface receptors with their activation and signal transduction mechanism recently identified. They have been associated with several metabolic functions yet their specific role in these processes remains enigmatic. As several Adhesion GPCRs are differentially regulated during adipocyte differentiation and between adipose tissue from lean and obese individuals we aim to study their contribution to these processes.
This PhD project requires experience in cell culture as well as basic molecular biology techniques (DNA and RNA extraction, PCR, reverse Transcription, qPCR). The successful candidate will isolate and work with primary cells, perform signal transduction assays in primary cells and cell lines and investigate adipocyte function by lipolysis, ELISA and metabolic analysis using the Seahorse technology.
Applicant must hold a Master’s or equivalent degree obtained in life sciences. Students are expected to work across disciplines and in cooperation with others. A capacity and willingness to integrate and collaborate is essential.
The Program provides a salary of 65 % of a German salary scale TVL-13. The project will start in spring 2017 but a certain degree of flexibility is possible.
To apply candidates should send a letter of motivation, Curriculum Vitae, and copies of education certificates as a single pdf-file to Ines Liebscher (firstname.lastname@example.org) by February 15th, 2017.